Le Samyn des Dames ended with a thrilling sprint finish, and it was Lotte Kopecky who clinched an inspired victory for Liv Racing.
The 25-year-old from Rumst, as noted on the Eurosport commentary of the finish, executed a brilliant burst that was "timed to perfection" to grab the win.
Kopecky, who finished fourth at Omloop Het Nieuwsblad last month, produced a brilliant performance to take the spoils.
Vuelta a Valencia
Kung claims Stage 4 time trial to take lead in Volta a Valencia GC
Emma Cecilie Norsgaard of Denmark finished in second place, 0.23 seconds adrift, while Australia's Chloe Hosking was third.
Kopecky bided her time expertly on the 92.5k route from Quaregnon to Dour in the one-day race.
Highlights: Kopecky storms to Le Samyn des Dames victory
Norsgaard (Movistar) and Hosking (Trek-Segafredo) did not quite have enough to resist Kopecky's surge to the line
Britain's Anna Henderson of Jumbo-Visma came in eighth place.
Le Samyn 2021 women's highlights - Catch up with everything from the race
- - -
Watch live cycling on Eurosport, eurosport.co.uk and the Eurosport app
Nibali surgery declared a success but Giro remains in doubt
Nibali unlikely to start Il Giro, but was this his final chance to win a third maglia rosa?