The CSC rider has four stage victories in the Giro d'Italia to his name, as well as three victories in the Vuelta a Espana.
Lombardi will bring down the curtain on a 14-year professional career, in which he has ridden for the likes of Lampre, Telekom and Acqua e Sapone.
Liquigas upstage Savoldelli's Astana
He moved to CSC in 2005, where he worked to protect team leader Ivan Basso in the peloton, and was the only rider in the Danish outfit to compete in all three grands tours in 2005, supporting Basso in the Giro and the Tour, and Carlos Sastre in the Vuelta.
Nibali takes second win in as many days
Saunier dominate Asturias