A US arbitration panel last year upheld findings by a French laboratory that Landis, 32, had used synthetic testosterone in winning the 2006 Tour.
"Floyd is happy to be moving forward and to have this opportunity to clear his name," Landis's attorney Maurice Suh said.
"We are confident that the evidence will prove his innocence and allow him to resume his racing career."
Tour de France
Slipstream ready for Tour challenge
21/03/2008 AT 14:44
The closed-doors hearing in New York for Landis, who was also banned from the sport for two years, is expected to take up to five days.
The International Cycling Union stripped Landis of his 2006 Tour de France crown after the arbitration ruling by a US Anti-Doping Agency panel last September, awarding the title to Spain's Oscar Pereiro.
Landis - who tested positive for synthetic testosterone after the penultimate stage in which he made a big comeback to reclaim the lead - has maintained his innocence, blaming procedural mistakes by the French laboratory.
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T-Mobile nine accused of doping
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