The 21-year-old impressed in United's Champions League win over CSKA Moscow this week before limping off with a thigh injury and has not been included for France's games on October 7 and 10.
Marseille forward Dimitri Payet, formerly of West Ham, is recalled to Les Bleus' squad along with as Tottenham midfielder Moussa Sissoko and Real Madrid defender Raphael Varane.
Marseille's French forward Dimitri Payet reacts
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Spurs goalkeeper Hugo Lloris, Arsenal duo Olivier Giroud and Laurent Koscileny and Chelsea midfielder N'Golo Kante are also included, with Paris St Germain's Kylian Mbappe, Juventus midfielder Blaise Matuidi and Atletico Madrid's Antoine Griezmann among the other big-name players selected.
Stoke's Kurt Zouma, Manchester United's injured Paul Pogba and Lyon's Nabil Fekir, who were all in Deschamps' previous squad, miss out.
France will face Bulgaria on October 7 before taking on Belarus three days later as they bid to secure their place in the tournament.
Les Bleus are top of qualifying Group A and lead Sweden by a point, with Holland four points adrift in third.
Reporting by PA Sport
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