Leeds and Millwall stunned, replay for holders Wigan

Goals from Scott Hogan and Ian Henderson gave the League Two underdogs a huge win over the 1972 cup winners at Spotland, while fellow fourth-tier side Southend saw off 10-man Millwall 4-1 in a delayed kick-off at Roots Hall.

Wigan - defending the trophy they won so memorably at Wembley against Manchester City last May - started strongly and were deservedly two goals up inside 25 minutes.

Roger Espinoza fired the opener on 18 minutes with a superb strike from fully 30 yards that flew into the top corner and when Jordi Gomez made it 2-0 shortly after it seemed not a matter of if but by how many.

However, Wigan failed to put the game to bed and were pegged back with two goals in the space of two minutes just before the interval.

First, Ben Reeves showed great footwork to beat Ali Al Habsi with a neat shot into the left-hand corner.

Reeves then repeated the feat by steering a cross from the left into the same corner with Al Habsi again helpless.

And the visitors squandered the opportunity to go in front just after the hour mark when James McClean fouled substitute George Baldock inside the area and the referee pointed to the spot.

Shaun Williams' connection was true enough, but Al Habsi was across to his right like a flash and made a superb diving stop.

Wigan looked to have made the most of their fortune when they regained the lead within seconds. Callum McManaman sprung the offside trap and composed himself before smashing past David Martin.

But the Dons were not finished and, with eight minutes remaining, Patrick Bamford fired home from close range to the delight of the away supporters behind the goal.

Aston Villa 1 - 2 Sheffield United

Barnsley 1 - 2 Coventry City

Bolton Wanderers 2 - 1 Blackpool

Brighton & Hove Albion 1 - 0 Reading

Bristol City 1 - 1 Watford

Doncaster Rovers 2 - 3 Stevenage

Everton 4 - 0 Queens Park Rangers

Grimsby Town 2 - 3 Huddersfield Town

Ipswich Town 1 - 1 Preston North End

Kidderminster Harriers 0 - 0 Peterborough United

Macclesfield Town 1 - 1 Sheffield Wednesday

Middlesbrough 0 - 2 Hull City

Newcastle United 1 - 2 Cardiff City

Norwich City 1 - 1 Fulham

Rochdale 2 - 0 Leeds United

Southampton 4 - 3 Burnley

Southend United 3 - 1 Millwall

Stoke City 2 - 1 Leicester City

West Bromwich Albion 0 - 2 Crystal Palace

Wigan Athletic 3 - 3 Milton Keynes Dons

Yeovil Town 4 - 0 Leyton Orient