| 1 | Lionel Messi
FC Barcelona | FC Barcelona | 36 | 34 |
| 2 | Cristiano Ronaldo
Real Madrid | Real Madrid | 27 | 26 |
| 3 | Luis Suárez
FC Barcelona | FC Barcelona | 33 | 25 |
| 4 | Iago Aspas
RC Celta | RC Celta | 34 | 22 |
| 5 | Cristhian Stuani
Girona FC | Girona FC | 33 | 21 |
| 6 | Antoine Griezmann
Atlético Madrid | Atlético Madrid | 32 | 19 |
| 7 | Maximiliano Gómez
RC Celta | RC Celta | 36 | 17 |
| 8 | Gareth Bale
Real Madrid | Real Madrid | 26 | 16 |
| - | Rodrigo
Valencia CF | Valencia CF | 37 | 16 |
| - | Gerard Moreno
RCD Espanyol | RCD Espanyol | 38 | 16 |
| 11 | Carlos Bacca
Villarreal CF | Villarreal CF | 35 | 15 |
| - | Willian José
Real Sociedad | Real Sociedad | 34 | 15 |
| 13 | Simone Zaza
Valencia CF | Valencia CF | 33 | 13 |
| - | Ángel
Getafe CF | Getafe CF | 33 | 13 |
| 15 | Santi Mina
Valencia CF | Valencia CF | 32 | 12 |
| - | Mikel Oyarzabal
Real Sociedad | Real Sociedad | 35 | 12 |
| 17 | Sergio León
Real Betis | Real Betis | 31 | 11 |
| - | Portu
Girona FC | Girona FC | 37 | 11 |
| 19 | Munir El Haddadi
Deportivo Alavés | Deportivo Alavés | 33 | 10 |
| - | Raúl García
Athletic Club | Athletic Club | 34 | 10 |
| - | José Luis Morales
Levante UD | Levante UD | 35 | 10 |
| 22 | Enis Bardhi
Levante UD | Levante UD | 26 | 9 |
| - | Wissam Ben Yedder
Sevilla FC | Sevilla FC | 25 | 9 |
| - | Paulinho
FC Barcelona | FC Barcelona | 34 | 9 |
| - | Aritz Aduriz
Athletic Club | Athletic Club | 33 | 9 |
| - | Adrián López
RC Deportivo | RC Deportivo | 30 | 9 |
| - | Jonathan Calleri
UD Las Palmas | UD Las Palmas | 37 | 9 |
| 28 | Antonio Sanabria
Real Betis | Real Betis | 17 | 8 |
| - | Loïc Rémy
Getafe CF | Getafe CF | 11 | 8 |
| - | Juanmi
Real Sociedad | Real Sociedad | 30 | 8 |
| - | Charles
SD Eibar | SD Eibar | 30 | 8 |
| - | Ángel Correa
Atlético Madrid | Atlético Madrid | 37 | 8 |
| - | Kike García
SD Eibar | SD Eibar | 35 | 8 |
| - | Léo Baptistão
RCD Espanyol | RCD Espanyol | 36 | 8 |
| - | Lucas Pérez
RC Deportivo | RC Deportivo | 35 | 8 |
| 36 | Loren Morón
Real Betis | Real Betis | 15 | 7 |
| - | Kevin Gameiro
Atlético Madrid | Atlético Madrid | 25 | 7 |
| - | Philippe Coutinho
FC Barcelona | FC Barcelona | 18 | 7 |
| - | Luís Muriel
Sevilla FC | Sevilla FC | 29 | 7 |
| - | Florin Andone
RC Deportivo | RC Deportivo | 29 | 7 |
| - | Isco
Real Madrid | Real Madrid | 30 | 7 |
| - | Ibai Gómez
Deportivo Alavés | Deportivo Alavés | 34 | 7 |
| - | Jorge Molina
Getafe CF | Getafe CF | 36 | 7 |
| - | Iñaki Williams
Athletic Club | Athletic Club | 38 | 7 |
| - | Daniel Parejo
Valencia CF | Valencia CF | 34 | 7 |
| - | Asier Illarramendi
Real Sociedad | Real Sociedad | 36 | 7 |
| 47 | Emmanuel Boateng
Levante UD | Levante UD | 25 | 6 |
| - | Enes Ünal
Villarreal CF | Villarreal CF | 23 | 6 |
| - | Marco Asensio
Real Madrid | Real Madrid | 32 | 6 |
| - | Samu Castillejo
Villarreal CF | Villarreal CF | 30 | 6 |