Joao Felix saw red for Atletico Madrid as Diego Simeone’s side drew 0-0 with Athletic Bilbao on Saturday night.
Antoine Griezmann was preferred ahead of Uruguayan striker Luis Suarez but the former Liverpool and Barcelona man replaced him shortly after the restart as the home side chased a winner.
Joao was almost the decisive scorer but was sent off after receiving a second yellow for dissent as he booted the ball into the crowd.
Both Real Madrid and Atletico Madrid have weekend matches postponed
- Opinion: Southampton draw highlighted City's biggest weakness
- Liverpool hit three to go top with win over Palace
- Odegaard striker secures much-needed win for Arsenal
Elsewhere, another former Atletico striker Radamel Falcao hit the net as he scored in his first appearance for Rayo Vallecano as they beat Getafe 3-0.
The 35-year-old, who also played for Galatasaray, Chelsea, Manchester United and Monaco in recent years, was a second-half sub.
"He's come wanting to help the team and to integrate as quickly as possible," said Rayo coach Andoni Iraola after the game.
"He's trained well, he's helped us and scored the goal that ended the game. We have to keep working with him. There are some ideas he has to adapt to but his own condition is very good."
Atletico Madrid ease to win over Barcelona to pile pressure on Koeman
'I'm still here' - Under-pressure Koeman tired of defending himself