Paris Saint Germain forward Kylian Mbappe will not play in Saturday's Ligue 1 game against Lens due to a calf injury, the French club said on Friday.
PSG trail City 2-1 after the first leg in Paris and Mauricio Pochettino's side will travel to Manchester for Tuesday's second leg.
Mbappe, 22, had recovered from a thigh injury to play in the first leg and played the full 90 minutes on Wednesday.
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The Frenchman is PSG's top scorer this season with 25 goals in the league and eight in Europe, which included a hat-trick against Barcelona at the Camp Nou.
PSG are second in the Ligue 1 standings, one point behind Lille with four games left in the season.

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