"It is a great satisfaction to be champions, especially knowing how difficult such a feat is to achieve," Ramos said after watching his side edge a nerve-shredding penalty shootout victory over fellow Spaniards Espanyol at Hampden Park.
The victory meant that Sevilla became the first side to make a successful defence of the UEFA Cup since Real Madrid in 1986.
"Winning this trophy is a weight off our shoulders and it will certainly help us approach the league and the Cup with even more optimism. Now let's see if we can bring another trophy to the club."
Sevilla followed up last season's crushing 4-0 victory over Middlesbrough in the UEFA Cup with a thrilling victory on Wednesday. Goalkeeper Andres Palop kept out three Espanyol spot-kicks as the holders won 3-1 in the shootout after the final had ended 2-2 after 120 minutes.
They are now on course to complete a remarkable treble. They have qualified for the final of the Copa del Rey against Getafe and are in third place in the Primera Liga, just two points behind leaders Real Madrid with four games left to play.
"It has been a marvellous year for us," said Ramos. "We started by beating Barcelona in the Super Cup and now we've qualified for another one."
Ramos paid tribute to opponents Espanyol, but felt his team had been the better side throughout the game and used their greater experience to maximum effect.
"At no time were we behind in the game," he said. "We had a lot of chances to score a third goal when we were 2-1 up, but they got the equaliser and that made for a very exciting penalty shootout.
"I think Sevilla were superior to Espanyol, though, because we created more chances and had more control. Having said that, Espanyol were great opponents and played very well especially after losing a player in the second half.
"Once you have penalties they are a lottery but I think our experience of having played in the final last year helped us. There is no way you can prepare for penalties in training, the pressure and tiredness isn't the same, but we had the experience and the players were brilliant, especially Palop."