Kevin De Bruyne may miss Belgium’s opening game of the Nations League on Saturday with his wife set to give birth to their third child.
De Bruyne did not join up with the rest of the squad when they assembled in Belgium on Tuesday to prepare for matches against Denmark in Copenhagen on Saturday and then Iceland in Brussels next Tuesday.
De Bruyne has permission to stay with his family and his participation will depend on the birth, added a Belgian football association spokesman.
Analysis: Naïve Belgium need a plan to beat Italy, and Martinez needs to adapt
- Transfer LIVE - James set for Everton, Havertz to Chelsea and more
- Manchester United will not give up on £100m Sancho - Paper Round
- The good times are returning to Arsenal - The Warm-Up
The squad have already been hit by the withdrawals of striker Divok Origi, goalkeeper Hendrik Van Crombrugge, defenders Dedryck Boyata and Elias Cobbaut and midfielder Nacer Chadli, who all reported injuries.
Defender Thomas Vermaelen was unable to travel from Japan because of COVID-19 pandemic restrictions.
Coach Roberto Martínez has only called up Ghent goalkeeper Davy Roef as cover.
Conte desperate to sign Kante for Inter - Euro Papers
Martinez 'quite positive' over De Bruyne, Hazard injuries ahead of Italy clash
Belgium can take a lot from Portugal win, but injuries to Hazard and De Bruyne are a worry