The German, who joined the tournament on a late wildcard, was beaten 3-6 7-5 7-6(5) by lucky loser Nicolas Jarry.
German world number three Zverev, who is looking to improve on his disappointing start to 2019, came back from a double break down in the third set but blew a match point at 6-5.

Alexander Zverev of Germany plays a backhand against Nicolas Jarry of Chile in their Men's round of 32 match during day two of the Barcelona Open Banc Sabadell at Real Club De Tenis Barcelona on April 23, 2019 in Barcelona, Spain.

Image credit: Getty Images

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It was the biggest win of the Chilean Jarry's career. The world number 81 will now face either Grigor Dimitrov or Fernando Verdasco in Thursday's third round.
Zverev's brother Mischa Zverev was also eliminated, going out 6-3 6-1 to David Ferrer in the first round, while Kei Nishikori eased to a 7-5 6-2 win over Taylor Fritz to secure a place in the third round.

Nicolas Jarry of Chile celebrates against Alexander Zverev of Germany in their Mens round of 32 match during day two of the Barcelona Open Banc Sabadell at Real Club De Tenis Barcelona on April 23, 2019 in Barcelona, Spain.

Image credit: Getty Images

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