The Frenchman, seeded sixth, went down tamely 6-2 6-3 to Russian Andrey Rublev.
Eighth seed Andreas Seppi of Italy beat another Frenchman, Jeremy Chardy, 7-5 2-6 6-4, and Spain’s Guillermo Garcia-Lopez beat Denis Kudla of the United States 7-5 6-4.
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ATP Monte Carlo
Tsitsipas happy to follow mother onto Monte Carlo honour roll
19/04/2021 AT 08:26
There were mixed results for the Australians on home turf with John Millman beating American Frances Tiafoe 4-6 7-6 (7/5) 7-5, but James Duckworth bowed out 3-6 6-3 6-4 to Hungary’s Marton Fucsovics.
At the ASB Classic in Auckland, David Ferrer’s farewell tour continued with a routine win over Robin Haase.
The 36-year-old Spaniard, who will retire in May, beat Dutchman Haase 6-2 6-1.
Germany’s Peter Gojowczyk edged past Guido Pella of Argentina 6-1 3-6 6-2 and Leonardo Mayer, also from Argentina, beat America’s Steve Johnson 7-5 6-3.
ATP Monte Carlo
Flawless Tsitsipas clinches maiden Masters title
18/04/2021 AT 15:49
ATP Monte Carlo
Nadal on rare clay defeat: 'I made lots of mistakes'
17/04/2021 AT 10:15