Arsenal start with summer signing Alexandre Lacazette up-front, but there's no place for Alexis Sanchez or Mesut Ozil in the matchday squad.
Chelsea have opted to stick with last season's winning formula, with all of their summer signings left out of the starting XI. Michy Batshuayi starts over record addition Alvaro Morata.
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Arsenal have beaten Chelsea on the last two occasions the pair have met at Wembley, with the Gunners winning last season's FA Cup Final 2-1 and also picking up a 1-0 win in the 2015 Community Shield.
However, Arsene Wenger's side have beaten the Blues in just one of their last 11 Premier League meetings.
Chelsea XI: Courtois; Azpilicueta, David Luiz, Cahill (c); Moses, Fabregas, Kante, Alonso; Willian, Batshuayi, Pedro.
Arsenal XI: Cech, Holding, Mertesacker, Monreal, Bellerin, Elneny, Xhaka, Oxlade-Chamberlain, Welbeck, Iwobi, Lacazette.
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