Lopez ends Nadal run

It was Nadal's first defeat since he lost to Andy Roddick in Miami on April 2, after which he embarked on a 24-match unbeaten sequence which included a fifth French Open on Sunday.

Lopez, one of the few players comfortable coming in after his first serve, kept world number one Nadal under pressure throughout the centre court contest and took his chances to claim the first victory for a Spaniard over Nadal since Juan Carlos Ferrero beat him in Rome two years ago.

Nadal showed no obvious signs of the muscle injury that required on-court treatment the day before but his precision groundstrokes were slightly off-beam on a slick court which suited Lopez's attacking style.

"I feel ready to go back home and enjoy a little bit with my family," Nadal, who showed no sign of the leg muscle injury that caused a pre-Wimbledon scare on Thursday, said.

"It's going to be a positive thing to enjoy a little bit of Mallorca weather, have dinner with friends and maybe play some golf. It's going to be very positive to help me go to Wimbledon with good motivation.

"When you play against big servers like Mardy Fish, Feliciano, the matches depend on a few points.

"Grass is not an easy surface and the first week on grass anything can happen."

Lopez will face American Fish in the semi-finals.